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Home > Rodents > How To Tell If a Pet Mouse Is Pregnant: 6 Vet Approved Signs

How To Tell If a Pet Mouse Is Pregnant: 6 Vet Approved Signs

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Mice are cute, relatively easy to care for, and can make great pets. They are also prolific breeders, with a female mouse potentially having 50 or more young in a single year. Whether you’re intentionally trying to breed mice to enhance the size of your mouse family, or are looking for signs of unwanted mouse pregnancy, knowing the signs to look for is beneficial. A mouse is pregnant for around 3 weeks before it gives birth, which means there is a reasonable window to determine pregnancy, and there are early signs to look for that are evident within the first day or so, as well as signs that occur during the late stages.

Below, we highlight six signs that you can look for when trying to determine whether a mouse is pregnant.


Mouse Pregnancy

Mice breed a lot. A female will become sexually active within the first 7 to 8 weeks of her life (though in same cases they may be sexually active at 4 weeks of age) with males becoming sexually active at around the same age. If you’re looking to avoid unwanted pregnancies in your mice, you will need to separate young litters before they are 3-4 weeks old.

A female mouse will go into heat every 4 or 5 days and remain in heat for about 15 hours and during this time, male mice in the vicinity will try and mate with her. If the mating is successful, gestation lasts for a period of 20 to 22 days and the litter, which consists of between three and 14 pups, will be delivered within 24 hours. The female can become pregnant with another litter even while nursing, but it is not advised that this be allowed to happen.

mice inside cage
Image By: Silvia, Pixabay

Signs To Look For

Whether unwanted or planned, pregnancy can occur at any time of the year, and you will need to have certain provisions and supplies ready for the arrival of a new litter. Determining pregnancy is important, and the following are signs that a mouse might be pregnant.

1. Look for a Plug

After mating, the male mouse leaves behind excess semen. This gathers at the junction of the female’s vagina and cervix and is meant to prevent further mating with other males. It can sometimes be seen at the opening of the vulva. The plug typically forms right after mating and will remain for 24 to 48 hours. The existence of a plug doesn’t necessarily mean that your mouse is definitely pregnant but it is a sign that mating has occurred. The plug may also be seen on the floor or in the bedding of the mouse’s cages.

gerbil mice in humans hand
Image By: Milada Vigerova, Pixabay

2. Nest Building

The next obvious sign is that the expectant mother will start nest building. Typically, she will look for a dark, secluded area, and will move comfortable nesting material to this spot. She will spend a lot of time in the area, getting the nest exactly how she wants it.

3. Swollen Abdomen

It isn’t always possible to see a visible difference in a pregnant mouse, especially if she is only carrying a small litter. In other cases, the swollen abdomen is obvious. This usually starts to occur about 10 days after mating, but it could be as late as 14 days, which means you only have a few days of preparation left.

Long hair Satin Mice
Image By: Sergey Bezgodov, Shutterstock

4. Prominent Nipples

At the same time as her belly grows, a pregnant mouse’s nipples may become more prominent. Again, this is a sign that the birth is only a few days away.

5. Behavioral Changes

A pregnant mouse’s behaviors may change during the pregnancy. She may avoid other mice, especially males in the same cage. She may also start to collect and store food, typically in the new nest that she is creating at the same time. If you know your mouse’s typical behavior, you will be able to spot these differences more easily.

mouse sitting on clay pot
Image By: Vladimir Turkenich, Shutterstock

6. Increased Appetite

It can be difficult to judge exactly how much a mouse is eating, but if you are filling the food bowl more often, or you notice your female mouse spending more time in and around the food bowl, this could be an indication of pregnancy.

Caring For Mom and Babies

If you haven’t already, you should remove the male mouse from the cage before the young are born. Although male mice aren’t known for eating their own young, you don’t want your mice mating and the mom getting pregnant again. Continuous pregnancies can cause a lot of physical and hormonal stress for the mom.

For the first week after your mouse has given birth, you shouldn’t disturb any of the family. Mom will provide for her young and the only time you should go in the cage is to fill the food bowl and check the water is fresh. After a week and by week two, the Pinkies will have grown fur and put on weight. They will look more like adults by this time. The babies should be weaned from their mom by the age of 3 to 4 weeks.

newborn mice
Image By: Live and Learn, Shutterstock



If you keep male and female mice together, there will come a time when your females are pregnant, and if you don’t separate them, this will continue to happen. Mice can breed at any time of the year, get pregnant while still nursing a litter, and they can produce as many as 50 young in a single year. Look for signs of pregnancy and ensure that mom and her young have everything they need to be comfortable and healthy.

Featured Image Credit: iliuta goean, Shutterstock

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